Commercial real estate is property that is used exclusively for business or commercial purposes such as office space; retail stores; warehouses; industrial space (buildings and manufacturing plants); hospitals; hotels and resorts; restaurants; shopping malls; and strip malls. Multifamily rental properties such as apartment complexes are also classified as commercial real estate.

Most commercial real estate is leased to tenants engaged in business or commercial activities. Commercial real estate is often an investment asset for real estate investment trusts (REITs) and large other investors.

In Indiana, commercial real estate encompasses properties used for business or commercial activities, including office spaces, retail stores, warehouses, industrial buildings, hospitals, hotels, restaurants, shopping centers, and multifamily rental properties like apartment complexes. These properties are typically leased to tenants for commercial operations. Indiana's regulations on commercial real estate leasing, zoning, and transactions are designed to ensure that these activities are conducted in a manner that is consistent with local planning and development goals. Commercial real estate can also be a significant investment asset, often held by real estate investment trusts (REITs) and other large investors. The state's laws govern the formation and operation of REITs, as well as the rights and obligations of landlords and tenants in commercial leasing arrangements. These laws are subject to both state statutes and federal regulations, which address aspects such as disclosure requirements, environmental compliance, and adherence to the Americans with Disabilities Act (ADA) for accessible design in commercial properties.