Commercial real estate is property that is used exclusively for business or commercial purposes such as office space; retail stores; warehouses; industrial space (buildings and manufacturing plants); hospitals; hotels and resorts; restaurants; shopping malls; and strip malls. Multifamily rental properties such as apartment complexes are also classified as commercial real estate.

Most commercial real estate is leased to tenants engaged in business or commercial activities. Commercial real estate is often an investment asset for real estate investment trusts (REITs) and large other investors.

In Iowa, commercial real estate encompasses properties used for business or commercial activities, including office spaces, retail stores, warehouses, industrial buildings, hospitals, hotels, restaurants, shopping centers, and multifamily rental properties like apartment complexes. These properties are typically leased to tenants for business purposes. The leasing, sale, and management of commercial real estate in Iowa are governed by a combination of state statutes and federal laws. Iowa's commercial real estate transactions are subject to state property laws, contract laws, and specific regulations that may govern commercial leasing. Additionally, zoning laws and local ordinances can significantly impact the use and development of commercial properties. Federal laws also play a role, particularly in areas such as environmental regulations, the Americans with Disabilities Act (ADA) compliance, and fair housing. Investors, including REITs, often hold commercial real estate as part of their investment portfolios, and these investments are subject to both state and federal securities laws.