Following a person’s arrest for a DUI/DWI criminal offense, police officers will ask the accused/defendant to submit to a blood test or blood draw in which a qualified person such as a nurse at the police station or hospital will draw the defendant’s blood (usually from the arm) into a vial to be tested for alcohol concentration and ultimately to determine whether the person is per se intoxicated. Per se intoxication is intoxication by definition—as defined in the state’s statutes, which is often a blood alcohol concentration (BAC) of .08 or higher.

All states have implied consent laws that make a driver’s consent or agreement to submit to a blood, breath, or urine test (a chemical test) when requested by a law enforcement officer a condition of the driver’s acceptance of a driver’s license offered by the state. Despite implied consent laws, in 2013 the United States Supreme Court held that if a person refuses to submit to having their blood drawn the police cannot draw the blood by force without a search warrant, as required under the Fourth Amendment to the United States Constitution. But more recently the Supreme Court upheld a nonconsensual blood draw of an unconscious person suspected of driving under the influence—based on the state’s implied consent laws and the exigent circumstances exception to the Fourth Amendment's warrant requirement.

And if a driver refuses to take a blood or breath test there are other consequences even if the police do not secure a search warrant for the blood draw—including admission of the refusal in evidence at trial, fines, penalties, and automatic suspension of the driver’s license for a year or more.

In Colorado, the law adheres to the concept of 'per se intoxication,' where a person is considered legally intoxicated if they have a blood alcohol concentration (BAC) of .08 or higher. Under Colorado's Express Consent Law, drivers have implicitly agreed to submit to a chemical test (blood, breath, or urine) if a law enforcement officer has reasonable grounds to believe the driver is under the influence of alcohol or drugs. Refusal to submit to a chemical test can lead to evidence of the refusal being used in court, as well as administrative penalties such as fines, mandatory alcohol education classes, and an automatic suspension of the driver's license, typically for one year for a first offense. Following the U.S. Supreme Court's rulings, Colorado law enforcement must obtain a search warrant to conduct a blood draw if a suspect refuses, unless the individual is unconscious or other exigent circumstances exist that would allow for a warrantless blood draw under the implied consent law.